The Effect of Topical Diltiazem on Post-Hemorrhoidectomy Pain: A Cohort Study

Background: Diltiazem is a calcium channel blocker that can prevent absorption by myocytes and decrease the tone of internal anal sphincter. Thus, it be used for treatment fissures; however, its effect on post-hemorrhoidectomy pain unclear. Accordingly, current study aimed to evaluate topical diltiazem pain. Methods: This cohort included 50 candidates hemorrhoidectomy referred Shahid Mohammadi Hospital, Bandar Abbas, Iran from March 20, 2020, 21, 2021. First, characteristics patients, including age, gender, degree hemorrhoid, number hemorrhoid pockets were recorded based purpose. One group received 2% three times day days after hemorrhoidectomy, other Vaseline®. Both groups also 500 mg paracetamol tablets. Post-hemorrhoidectomy was assessed using numerical rating scale (NRS) patients first third surgery. The cumulative amount consumed noted day. Results: Patients in both comparable regarding hemorrhoids, pockets. There no significant difference between terms surgery (P=0.626), while mean score significantly lower compared placebo (P<0.001). Finally, higher (P=0.001). Conclusion: Overall, appears more effective than reduction.